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(2)
By Target- Apoptosis
- NF-κB(1)
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By Target By ResearchField- Cancer(2)
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Results for "
db1976
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- DB1976T109641557397-51-9In houseDB1976 is a selenophene analog of DB270 and a highly potent, cell-permeable, fully efficacious transcription factor PU.1 inhibitor. It effectively inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. Additionally, DB1976 has an apoptosis-inducing effect.
- $118
SizeQTY - DB1976 dihydrochlorideDB1976 hydrochloride, DB1976 2HClT10964L2369663-93-2DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
- $390
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