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Results for "
dabigatran etexilate
" in TargetMol Product Catalog- Inhibitors & Agonists4
Dabigatran etexilate
BIBR 1048
T0389211915-06-9
Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor that binds to thrombin, blocking its thrombogenic activity and preventing thrombus formation.
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Dabigatran Etexilate Mesylate
BIBR 1048MS, Dabigatran etexilate methanesulfonate
T5133872728-81-9
Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).
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BIBR 1087 SE
Desethyl Dabigatran Etexilate
T19208212321-78-3
BIBR 1087 SE (Desethyl Dabigatran Etexilate) is a metabolite of dabigatran etexilate.
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Dabigatran Acyl-β-D-Glucuronide
T359391015167-40-4
Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.
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