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By Target- Calcium Channel
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Results for "
d600
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Inhibitory Antibodies1
KD6001
T9901A-17472983061-18-1
KD6001 is a humanized IgG1κ monoclonal antibody targeting CTLA4. It effectively disrupts the interaction between CTLA-4 and CD80 (IC50: 16 ng/mL) as well as CD86. KD6001 enhances the expression of IL-2 and IFNγ in PHA-activated human lymphocytes, demonstrating potent antitumor activity. It significantly inhibits tumor growth in mouse models with MC38, B16, and Hepa1-6 tumors. KD6001 is applicable in cancer research, including studies on advanced melanoma, hepatocellular carcinoma, and liver cancer.
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