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By Target- PI3K
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Results for "
cyh 33
" in TargetMol Product Catalog- Inhibitors & Agonists1
CYH33
T389781494684-28-4
CYH33, an orally active and highly selective PI3Kα inhibitor, demonstrates specificity with IC50 values of 5.9 nM for the α isoform, 598 nM for β, 78.7 nM for δ, and 225 nM for γ. It effectively inhibits Akt and ERK phosphorylation and induces substantial G1 phase arrest in breast cancer and non-small cell lung cancer (NSCLC) cells, showcasing potent activity against solid tumors.
- $797
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