cyclo-(pro-gly)

Cyclo-(Pro-Gly) is an alkaloid with weak antibacterial activity and antioxidant properties that can inhibit Chitinase B and scavenge free radicals. It is widely used in biochemical experiments and drug synthesis research.

TRAP-6 amide, a PAR-1 thrombin receptor agonist peptide, [Cyclo(Pro-Arg-Gly)-Arg-Ser-Gly], is derived from the primary sequence of [TRAP-2].

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin on Caco-2 cells [1].

Cyclo(Gly-Pro) is a cyclic dipeptide derived from the N-terminus of IGF-1. It has been shown to alleviate pain behaviors and inflammatory responses in mice.

Cyclo(Gly-L-Pro), a cyclic dipeptide, demonstrates significant immunomodulatory activity by stimulating beneficial immune responses while simultaneously suppressing the release of the pro-inflammatory cytokine TNF-α, reducing mRNA expression of IL-1β and IL-6, and inhibiting nitric oxide (NO) production. it has also been shown to enhance memory and improve functional recovery in animal models, indicating substantial potential for neuroscience research due to its neuroprotective and immunostimulatory properties.

Cyclo(Pro-Hyp) is a cyclic dipeptide derived from collagen. Its related collagen breakdown product, Gly-Pro-Hyp, can enhance the growth of skin fibroblasts and is involved in tissue reconstruction, exhibiting biological activity.