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(1)
By Target- Androgen Receptor
- Apoptosis(1)
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Results for "
csrm617 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists1
CSRM617 hydrochloride
CSRM617 hydrochloride(787504-88-5 Free base)
T10896L1353749-74-2In house
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor), with a Kd of 7.43 µM in SPR assays, directly binding to the OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP and is well tolerated in the mouse model of prostate cancer [1].
- $35
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T10896787504-88-5
CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2, the main regulator of androgen receptor). The Kd in SPR analysis is 7.43 uM, which can directly bind to the OC2-HOX domain. CSRM617 induces apoptosis by cleaving the
- $1,520
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