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Results for "
cs 461
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- CS 461CS-461, CS461T31104115948-58-8CS 461 is a cephalosporin antibiotic that has shown effective antimicrobial activity against a variety of bacteria in vitro and in vivo.
- $1,520
SizeQTY - IACS-4619T2180411884209-98-6IACS-4619 (compound 4) is a highly selective 2-aminopyridine-based MTH1 (MutT homolog 1) inhibitor with an IC50 of 0.2 nM. By inhibiting MTH1 from hydrolyzing oxidized purine nucleotides like 8-oxo-dGTP, it prevents MTH1 from stopping the incorporation of these nucleotides into DNA. In MTH1-overexpressing U2OS cells, IACS-4619 significantly inhibits endogenous MTH1 activity, yet it shows no substantial antiproliferative or cytotoxic effects on various human cancer or normal cell lines. IACS-4619 can be utilized for MTH1-targeted research within the field of oncology.
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