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(2)
By Target- ALK
- c-Met/HGFR(2)
- Autophagy(1)
- ROS(1)
- ROS Kinase(1)
- Trk receptor(1)
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Results for "
crizotinib hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists2
Crizotinib hydrochloride
PF-02341066 hydrochloride
T83991415560-69-8
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met, with IC50 values of 20 nM and 8 nM, respectively.
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Ensartinib hydrochloride
Ensartinib dihydrochloride, X-396 dihydrochloride
T223242137030-98-7
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
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