cholesteryl

Cholesteryl arachidonate is a human endogenous metabolite.

Cholesteryl Linolenate is a human endogenous metabolite.

Cholesteryl Lignocerate is a cholesterol ester that can be hydrolysed by acid lipases.

Cholesteryl erucate, a cholesterol ester, serves as a standard for the quantification of cholesterol esters in human meibomian gland secretions.

Cholesteryl trans-9-hexadecenoate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Cholesteryl elaidate is an organic compound classified as an ester. It is formed through a reaction between cholesterol and elaidic acid, resulting in a white crystalline solid with a mild sweet taste. In the pharmaceutical industry, cholesteryl elaidate has numerous applications, particularly as a bioactive compound with potential research roles for addressing various medical conditions such as high cholesterol and inflammation-related diseases. Additionally, it has potential use as a food additive to enhance texture and stability.

Cholesteryl n-butyrate is a cholesterol ester formed from two naturally occurring substances: cholesterol and butyric acid. It can be utilized in synthesizing solid lipid nanoparticles (SLN) that inhibit the adhesion and migration of colon cancer cells, thus serving as a delivery system for the anticancer agent butyrate esters.

Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl Hemisuccinate inhibits the hepatotoxicity of acetaminophen and prevents AAP-induced apoptosis and necrosis in hepatocytes. Cholesteryl Hemisuccinate inhibits DNA polymerase and DNA topoisomerase, thereby inhibiting DNA replication and repair as well as cell division.

Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a combination of steroid and alcohol) and a lipid found in the cell membranes of all body tissues and transported in the blood plasma of all animals. The accumulation of cholesterol esters in the arterial intima (the innermost layer of an artery, in direct contact with the flowing blood) is a characteristic feature of atherosclerosis. Atherosclerosis is a disease affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part to the deposition of lipoproteins (plasma proteins that carry cholesterol and triglycerides).

Cholesteryl linoleate is the major cholesteryl ester in LDL and atherosclerotic lesions. It is present in LDL as a cholesteryl ester that is oxidized to form cholesteryl linoleate hydroperoxides using LDL receptor-associated proteins that are transferred to the plasma membranes of macrophages and CHO cells expressing 15-lipoxygenase.

Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activates multiple protein kinase C (PKC) iso-enzymes, especially the ε, η and ζ isoforms.

Cholesteryl formate (3beta-Acetoxy-cholest-5-ene), the first compounds to be isolated from red algae, is a cholesteryl ester.

Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol.

Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach.

Cholesteryl isoamyl ether is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Cholesteryl (pyren-1-yl)hexanoate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Cholesteryl-PEG1000-Biotin is a lipid product with a cholesterol backbone linked to a PEG unit on one end and a biotin unit on the other. Biotin (Biotin) is an enzyme cofactor useful for protein labeling, while PEG is a low-toxicity hydrophilic polymer. Cholesteryl-PEG1000-Biotin is applicable in drug circulation time studies.

Cholesteryl-PEG2000-Biotin (Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate) is a lipid compound. It consists of a cholesterol skeleton linked to a PEG unit on one end and a biotin unit on the other. Biotin is a coenzyme factor used to label proteins, while PEG is a low-toxicity hydrophilic polymer. Cholesteryl-PEG2000-Biotin can be applied in drug circulation time studies.

Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor designed to reduce the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. It failed in phase III trials due to an excess of deaths.

Cholesterol is the primary sterol in mammals, accounting for approximately 20–25% of the plasma membrane structure. It plays a key role in regulating membrane fluidity, permeability, and protein function. As an endogenous agonist of estrogen-related receptor α (ERRα), cholesterol is widely involved in metabolic regulation and serves as a precursor for the synthesis of hormones and bile acids. It is commonly used in experimental models of hyperlipidemia.

Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the inward-rectifier potassium ion channel.

CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM).

Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.

DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent manner.DC-Chol hydrochloride induces an improved and balanced immunity, which could contribute to hepatitis B vaccine research.