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By Target- Chk
- Trk receptor(1)
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Results for "
chk1 in 6
" in TargetMol Product Catalog- Inhibitors & Agonists3
Chk1-IN-6
Chk1-IN-6
T400912428423-77-0
Chk1-IN-6 is a potent, selective, and orally bioavailable [CHK1] inhibitor candidate.
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Multi-kinase-IN-6
T81740
Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that impedes the activity of TrkA, ALK2, c-KIT, EGFR, PIM1, CK2α, CHK1, and CDK2. It exhibits antiproliferative effects on MCF7, HCT116, and EKVX cancer cell lines with IC50s of 3.36 μM, 1.40 μM, and 3.49 μM, respectively. Additionally, Multi-kinase-IN-6 induces cell cycle arrest at the G1 S and G1 phases in MCF7 and HCT116 cells, respectively, and effectively triggers apoptosis [1].
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