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cdk-4/6-in-3

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
CDK4/6-IN-3
T107372366237-37-6
CDK4/6-IN-3, a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM), is used for the treatment of glioblastoma and inhibits CDK1 with a Ki of 110 nM.
  • $4,020
3-6 months
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VEGFR-2-IN-69
T210956
VEGFR-2-IN-69 (Compound 5A) is an inhibitor of VEGFR-2 and telomerase (Telomerase) that enhances the expression of caspase 3, caspase 8, and caspase 9, while reducing the levels of CDK-2, CDK-4, and CDK-6. It has an IC50 of 15.46 µM against HCT116.
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