canthin-6-one

Canthin-6-one (NSC 103003)is an alkaloid isolated from Allium neapolitanum with antibacterial activity and inhibitory effect against Mycobacterium tuberculosis.

5-Hydroxy-canthin-6-one is a natural product for research related to life sciences. The catalog number is TN3122 and the CAS number is 64118-73-6.

Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities.

Canthin-6-one 9-O-galactoside is an alkaloid compound.

9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1-4 μg mL.

11-Hydroxy-canthin-6-one has antineoplastic activity.

1-Hydroxy-9-medroxycanthin-6-one is a natural product for research related to life sciences. The catalog number is TN2537 and the CAS number is 622408-85-9.

1-Hydroxycanthin-6-one is a natural product of Picrasma, Simaroubaceae. The catalog number is TN2542 and the CAS number is 80787-59-3. 1-Hydroxycanthin-6-one can be used as a reference standard.

10-Hydroxycanthin-6-one has potential to be an antimicrobial agent. 10-Hydroxycanthin-6-one has in vitro antimalarial activity; it also has cytotoxic activity, it could be a plant anticancer agent.

4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity against Staphylococcus aureus and its drug-resistant strains. It is a potent, non-competitive inhibitor of CYP1A2-mediated phenacetin O-deethylation (IC50: 1.7 μM, Ki: 2.6 μM) and a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase. Additionally, it exhibits cytotoxicity to tumor cell lines U937 and HepG2.

4,9-Dimethoxycanthin-6-one is a natural product from Ailanthus altissima.

5-Methoxycanthin-6-one displays moderate cytotoxic activity against the human prostate cancer cell PC-3 line, with IC50 values ranging from 13.5-15.4 uM versus doxorubicine with IC50 = 1.5 uM. It also exhibits a clear suppressive effect on the phagocytosi

9,10-Dimethoxycanthin-6-one shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 5.0 microM).

9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilization.9-Hydroxycanthin-6-one inhibits Wnt signaling through the activation of GSK3β independent of CK1α.

9-Methoxycanthin-6-one-N-oxide shows cytotoxic activity against a panel of cell lines comprising a number of human cancer cell types.

4-Methylthiocanthin-6-one is an alkaloid found in P. australis.