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cac-253

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • Peptide Products
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    TargetMol | Peptide_Products
  • cAC 253
    TP2135
    Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's disease model.
    • $711
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  • cAC 253 acetate
    TP2135L
    cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM.
    • $195
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  • Cyclic AC253
    TP3648
    Cyclic AC253 is an amylin receptor antagonist with an IC50 of 0.3 μM. It offers neuroprotective effects against Aβ toxicity and mitigates Aβ-induced impairments in hippocampal long-term potentiation. Additionally, Cyclic AC253 is capable of penetrating the blood-brain barrier.
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