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By Target- Phospholipase
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Results for "
ca2+-independent phospholipase a2
" in TargetMol Product Catalog- Inhibitors & Agonists3
ONO-RS-082
T2181599754-06-0
ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor.
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pacocf3
Palmityltrifluoromethylketone, 1,1,1-trifluoroheptadecan-2-one
T21907141022-99-3
PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2].
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GK563
T735272351820-19-2
GK563, a selective Ca 2+-independent phospholipase A2 (GVIA iPLA2) inhibitor, exhibits a potent IC50 value of 1 nM and demonstrates 22,000-fold greater activity against GVIA iPLA2 compared to GIVA cPLA2. Its efficacy in reducing β-cell apoptosis triggered by proinflammatory cytokines suggests potential therapeutic benefits in combating autoimmune disorders, including type 1 diabetes.
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