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Results for "
c48/80
" in TargetMol Product Catalog- Inhibitors & Agonists2
Compound 48/80 trihydrochloride
C48 80 trihydrochloride
T13623848035-21-2
Compound 48 80 trihydrochloride (C48 80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction. It acts as a mast cell degranulator and histamine releaser and inhibits phosphatidylinositol-specific phospholipase C activity in human platelets.
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GE1111
T2056682883669-12-1
GE1111 is an antagonist of the mas-related G protein-coupled receptor X2 (MRGPRX2), exhibiting an IC50 of 9.42 μM. It inhibits mast cell degranulation with an IC50 of 4.7 μM. In the C48 80-induced systemic allergic reaction model, GE1111 demonstrates both antiallergic and anti-inflammatory properties.
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