c-jun peptide

Peptide comprising residues 33 - 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Spec

JIP-1(153-163) is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). JIP-1(153-163) binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.

JIP-1 (153-163) acetate(438567-88-5 free base) is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). JIP-1 (153-163) acetate(438567-88-5 free base) binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.

CMX-8933 is an 8-peptide fragment of the goldfish brain neurotrophic ependymin protein. This compound enhances the enzymatic activity of c-Jun N-terminal kinase (JNK), promotes the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 is utilized for investigating the role of ependymin proteins in neural plasticity, learning, memory formation, and neural regeneration.

HE4-1 leech peptide is a p38 MAPK inhibitor with additional c-Jun N-terminal kinase (JNK) inhibitory properties. It can suppress macrophage migration without significantly affecting the phagocytic ability, lysozyme activity, or expression levels of various inflammatory factors in macrophages. HE4-1 leech peptide is applicable for atherosclerosis research.