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busulfan

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Busulfan
Sulphabutin, Myleran, Busulphan
T092355-98-1
Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.
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Busulfan-d8
Sulphabutin-d8, Myleran-d8, Busulphan-d8
TMID-0076116653-28-2
Busulfan-d8 (Sulphabutin-d8) is a deuterated Busulfan. Busulfan is an effective alkylating anticancer agent with immunosuppressive and myeloablative activities. It exerts anti-cancer activity by crosslinking DNA and causing DNA damage.
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7-10 days
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