bufuralol

Bufuralol (Ro 3-4787) is an orally active β-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.

Bufuralol hydrochloride belongs to the class of beta-adrenoreceptor antagonists and is a potent, orally active, non-selective beta-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a prototypical CYP2D6 probe substrate (Km = 5-50 microM) and is extensively used in biochemical studies to characterize CYP2D6 enzymatic activity and evaluate genetic variants.

1'-Hydroxy bufuralol is a metabolite of bufuralol, an orally active β-adrenoceptor blocker used in the study of hypertension and cardiac arrhythmias.

Bufuralol-D9 hydrochloride is the deuterated form of Bufuralol Hydrochloride (T21684) and can be used for isotope tracing.

1-Hydroxybufuralol-D9 is the deuterated form of 1-Hydroxybufuralol (T41364) and can be used for isotope tracing.

1`-Hydroxybufuralol (Standard) is a reference standard of 1`-Hydroxybufuralol intended for quantitative analysis, quality control, and related biochemical research applications.

Ro 3-7410 is an active hydroxy metabolite of bufuralol.