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bsj 03204

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    TargetMol | PROTAC
BSJ-03-204
BSJ03204
T306002349356-09-6
BSJ-03-204 is a selective Cdk4/6 degrader.
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BSJ-03-204 triTFA
T77923
BSJ-03-204 triTFA is a potent and selective Cereblon- and CDK-targeted PROTAC (PROteolysis TArgeting Chimera) featuring Palbociclib-based ligands for the degradation of CDK4/6. It exhibits IC50 values of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1, indicating strong inhibitory capabilities. Notably, it spares IKZF1/3 from degradation and possesses anti-cancer activity [1].
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