bq3020 tfa (143113455 free base)

BQ-3020 (TFA) is a selective ETB receptor agonist that inhibits [125I] et-1 binding to the ETB receptor in the cerebellum with a 0.2nm IC50, causing vasoconstriction.

BQ-3020 (TFA) is a selective ETB receptor agonist that inhibits [125I]ET-1 binding to the ETB receptor in the cerebellum with an IC50 of 0.2 nM and induces vasoconstriction [1].

BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2 nM and induces vasoconstriction in rabbit pulmonary arteries. Additionally, it promotes relaxation of the pig urinary bladder neck, rendering it useful for research into cardiovascular diseases [1] [2].