bodipy-cholesterol

BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake and interorganelle sterol flux.

BODIPY-cholesterol conjugate-1 (compound 5), a BODIPY-cholesterol conjugate, serves as an effective probe for the simultaneous visualization of intracellular cholesterol pools and monitoring cholesterol efflux from cells to extracellular acceptors [1]. It exhibits an excitation wavelength (λex) of 541 nm and an emission wavelength (λem) of 615 nm.

BODIPY-cholesterol conjugate-2 (compound 6), a BODIPY-cholesterol conjugate, serves as an efficient probe for the simultaneous visualization of intracellular cholesterol pools and monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) [1].

BODIPY-cholesterol conjugate-3 (compound 7) serves as an analog to cholesterol featuring a fluorescent BODIPY group. This compound is primarily localized to the plasma membrane [1] and facilitates the visualization of multiple cholesterol pools within cells.

BODIPY 480 508-cholesteryl linoleate is a cell-permeable and fluorescently tagged derivative of Cholesteryl Linoleate, utilized for monitoring cholesterol transport in isolated human monocyte-derived macrophages (Ex Em=480 508 nm).