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bms-984923

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  • Inhibitors & Agonists
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BMS-984923
BMS984923, BMS 984923
T387891375752-78-5
BMS-984923 is an orally available and blood-brain barrier permeable mGluR5 silencing allosteric modulator that inhibits β-amyloid oligomer-induced aberrant synaptic signaling, and can be used to study Alzheimer's disease.
    7-10 days
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    (S,S)-BMS-984923
    T741851375752-77-4
    (S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923, exhibiting an EC50 >1μM for the mGluR5 receptor [1]. BMS-984923, in contrast, is a potent mGluR5 silent allosteric modulator [2].
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