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By Target- Endothelin Receptor
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bms-182874 hydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- BMS 182874 hydrochlorideT217901215703-04-0BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.
- $74
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- BMS 182874
BMS-182874, BMS182874T26841153042-42-3BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 μM for ETA and a Ki value of 0.055 μM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.- $30
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