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By Target- HIV Protease
- gp120/CD4(1)
- Others(1)
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Results for "
bms 378806
" in TargetMol Product Catalog- Inhibitors & Agonists3
BMS 378806
T69371357263-14-0
BMS-378806 is an orally bioavailable HIV-1 inhibitor that interferes with gp120-CD4 interaction.
- $1,520
Size
QTY
BMS-378806
BMS-806, BMS378806
T6418357263-13-9
BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
- $30
Size
QTY
DS-003
DS003, DS 003, BMS-599793, BMS599793, BMS 599793
T202020676489-50-2
DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.
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