biotin peg4 amine

Biotin-PEG4-amine is a biotinylated PEGylated amine linker that provides a flexible spacer suitable for PROTAC synthesis and bioconjugation workflows. Biotin-PEG4-amine facilitates efficient ligand attachment to proteins or small molecules via its terminal amine while preserving accessibility for streptavidin-based detection or enrichment techniques.

NHS-PEG4-biotinidase resistant biotin is a biotinylation reagent featuring a terminal NHS ester. The hydrophilic PEG spacer enhances its solubility in aqueous media. NHS ester is suitable for labeling primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Biotin-PEG4-SS-acid functions as a cleavable reagent designed to efficiently attach biotin to amine-containing biomolecules. The disulfide bond within this linker can be cleaved using reducing agents [such as DTT, BME, and TCEP] to remove the biotin label.