biocytin

Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ϵ-amine of L-lysine via a secondary amide bond.

N-(Azido-PEG4)-biocytin serves as a PEG-based PROTAC linker for PROTAC synthesis[1].

N-(Propargyl-PEG4)-biocytin is a polyethylene glycol (PEG)-based linker designed for constructing proteolysis targeting chimeras (PROTACs) [1].

Biocytin-β-endorphin, human is a biotin-labeled version of β-endorphin, human. β-Endorphin, human, an essential endogenous peptide found in the pituitary and hypothalamus, acts as an opioid receptor agonist with greater affinity for μ-opioid and δ-opioid receptors. It is known for its pain-relieving properties.

p-Diazobenzoyl-biocytin chloride is a biotin derivative used for labeling tyrosine and histidine residues in peptides and proteins.

N-Boc-Biocytin is a biotin PEG linker that incorporates both a carboxyl group and a Boc-protected amine. The carboxyl group reacts with a primary amine (-NH2) to form a stable, irreversible amide bond. The Boc group can be removed under acidic conditions to yield a free amine suitable for further conjugation.

Biocytin hydrazide is an aldehyde-fixable cellular tracer that can be introduced into cells by microinjection. Biocytin hydrazide can also be used to label glycoproteins or other carbohydrate molecules.