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(2)
By Target- BCL6
- Bcl-2 Family(1)
- Bcl-6(1)
- CDK(1)
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Results for "
bi-3812
" in TargetMol Product Catalog- Inhibitors & Agonists3
BI-3812
T145612166387-64-8
BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50: 3 nM). BI-3812 also has antitumor activity.
- $112
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EB-TCIP
BAK-04-212
T206944
EB-TCIP (BAK-04-212) is a bivalent molecule composed of AP1867 and BI-3812. It facilitates the reversible formation of a ternary complex between FKBPF36V and BCL6BTB, thereby recruiting FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, rapidly inducing expression of BCL6 target genes such as SOCS2 and CXCL11. EWS/FLI1 is a fusion transcription factor found in Ewing sarcoma. EB-TCIP is applicable for studying transcriptional dysregulation in cancer.
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