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(2)
By Target- Bcl-2 Family
- Apoptosis(1)
- Caspase(1)
- EGFR(1)
- Raf(1)
- Others(1)
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By Target By ResearchField- Cancer(1)
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Results for "
bcl-6-in-4
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Recombinant Protein1
- BCL6-IN-4BCL6-IN-4T364842253879-65-9BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].
- $1,900
SizeQTY - EGFR/BRAFV600E-IN-6T213818EGFR/BRAFV600E-IN-6 (Compound 7c) is a dual inhibitor of EGFR and BRAFV600E, with IC50 values of 0.12 μM and 0.05 μM, respectively. It exhibits antiproliferative activity against HT-29, MCF-7, A549, and Panc-1 cells, with IC50 values of 8, 4, 6, and 7 μM. EGFR/BRAFV600E-IN-6 activates caspase-3/8/9, upregulates Bax expression, and downregulates Bcl-2 levels, inducing apoptosis and exhibiting antioxidant properties. It is applicable in cancer research, such as studies on colon cancer.
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