basic yellow-1

Thioflavin T (Basic Yellow 1) is a widely used dye for visualizing and is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections.

LysoTracker Yellow HCK 123 is a highly selective fluorescent probe designed for labeling acidic organelles in live cells, particularly lysosomes. The probe accumulates in acidic compartments via its weak base moiety. In plant sciences, it has been discovered to specifically label silica-deposition vesicles (SDVs) in diatoms, serving as a vital tool for studying biosilicification. In pharmacological research, it is frequently utilized to track the intracellular localization of drug delivery systems (e.g., polymeric micelles) to verify endocytosis and trafficking pathways through colocalization analysis.

The cell-permeant pH indicator, carboxy SNARF-1, acetoxymethyl ester, acetate (CAS #126208-13-7) has a pKa of ~7.5 after de-esterification, thus is useful for measuring pH changes between pH 7 and pH 8. Carboxy-SNARF-1 exhibits a significant pH-dependent