azure b

Azure B (Azure B chloride) is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and 968 nM for recombinant human MAO-A and MAO-B).

Azure B eosinate is a versatile dye used extensively in biological experiments to assist researchers in observing cell structures, tracking biomolecules, evaluating cell functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications span basic scientific research to clinical diagnostics. In addition to these scientific uses, dyes are crucial in traditional areas like textile dyeing, as well as in emerging fields such as functional textile processing, food pigments, and dye-sensitized solar cells.

Azure B (Standard) is the standard of Azure B (T18918), suitable for research related to quantitative analysis, quality control, and biochemical experiments. Azure B is a phenothiazine cationic dye and the key active metabolite of methylene blue in vivo. It has two main application directions: as a core component of Romanowsky-Giemsa stain, forming charge-transfer complexes with Eosin Y on target substrates, producing a purple color in stained biological samples (the "Romanowsky-Giemsa effect"), which is a key mechanism for identifying cells and pathogens in fields such as hematopathology and microbiology; and as a potent, reversible, and selective inhibitor of monoamine oxidase A (MAO-A) (IC50 = 11 nM for human recombinant MAO-A, 968 nM for MAO-B).

Azure C, the product of sequential enzymatic oxidation of Methylene blue (MB) or Azure B (AB), serves as the substrate of horseradish peroxidase (HRP) [1] [2].