azide-peg-amine

Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG)-derived linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) linker compound, designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].

Azide-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-derived linker compound with azide functionality, primarily utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N3-PEG-NH2 (MW 1000) (Azide-PEG-Amine (MW 1000)) is a heterobifunctional PEG compound featuring azide and amine groups at the termini of the PEG chain. Serving as a crucial crosslinker with a PEG chain, the azide group allows for molecular conjugation via chemical reactions, while the amine group can react with carboxylic acids or NHS esters.

N3-PEG-NH2 (MW 10000) (Azide-PEG-Amine (MW 10000)) is a heterobifunctional PEG compound featuring an azide and an amine group at each end of the PEG chain. This compound serves as a crucial crosslinker with PEG linkages. The azide group facilitates molecular conjugation through chemical reactions, while the amine group can react with carboxylic acids or NHS esters.

N3-PEG-NH2 (MW 3400) (Azide-PEG-Amine (MW 3400)) is a heterobifunctional PEG compound featuring azide and amine groups at its termini. This compound serves as a significant crosslinker with a PEG chain. The azide group allows for molecular conjugation through chemical reactions, while the amine group reacts with carboxylic acids or NHS esters.

N3-PEG-NH2 (MW 20000) is a bifunctional PEG product featuring an azide group and an amino group at the PEG terminus, offering excellent water solubility, biocompatibility, and low immunogenicity. N3-PEG-NH₂ (MW 20,000) is an important cross-linking agent; the azide group can be used in click chemistry, while the amine group can react with carboxylic acids or NHS esters.

N3-PEG-NH2 (MW 40000) [Azide-PEG-Amine (MW 40000)] is a heterobifunctional PEG compound featuring an azide group and an amine group at its termini. This compound serves as an essential crosslinking agent with a PEG chain. The azide moiety can participate in chemical reactions for molecular conjugation, while the amine group can react with carboxylic acids or NHS esters.

N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker used in PROTAC synthesis [1].

Propargyl-PEG3-amine is a PEG derivative containing a propargyl group and an amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Propargyl-PEG7-amine is a PROTAC linker belonging to the PEG class and is utilized in the synthesis of PROTAC molecules. It serves as a click chemistry reagent, featuring an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with azide-containing molecules.

Propargyl-PEG11-amine is a PEG-based PROTAC linker employed in the synthesis of PROTAC molecules. Serving as a click chemistry reagent, it incorporates an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules containing azide groups.

DBCO-PEG6-amine (TFA) is a PROTAC linker classified within the PEG category, suitable for synthesizing PROTAC molecules. This compound is utilized as a click chemistry reagent and includes a DBCO group, enabling it to participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules.

Sulfo DBCO-PEG3-acid is a click chemistry reagent featuring an azide group. This compound is an analog of DBCO-acid, equipped with a PEG linker and a DBCO moiety. The DBCO group, known for its strain-promoted high-energy state, is commonly utilized in copper-free click reactions. The hydrophilic polyethylene glycol chain and the sulfonyl group enhance its water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (such as EDC or HATU) to form stable amide bonds. This reagent is for research use only and is of reagent grade.

N3-PEG-NH2 (MW 2000) (Azide-PEG-Amine (MW 2000)) is a heterobifunctional PEG compound that features azide and amine groups at the termini of the PEG chain. It serves as a crucial crosslinker with a PEG backbone. The azide group can participate in molecular conjugation via chemical reactions, while the amine group reacts with carboxylic acids or NHS esters.

N3-PEG-NH2 (MW 5000) (Azide-PEG-Amine (MW 5000)) is a heterobifunctional PEG product featuring azide and amine groups at the ends of the PEG chain. This compound serves as a crucial crosslinking agent with a PEG chain. The azide allows for molecular conjugation through chemical reactions, while the amine can react with carboxylic acids or NHS esters.

Azido-PEG13-amine (Azido-PEG13-NH2) is a PEG derivative used in research areas like drug delivery. It functions as a click chemistry reagent, containing an Azide group that enables copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it participates in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

DBCO-PEG-Amine (MW 3400) (DBCO-PEG-NH2 (MW 3400)) is a PEG derivative composed of DBCO, PEG units, and an amine group. The amine group can react with other chemical groups, such as carboxyl or aldehyde groups, to form stable chemical bonds. Additionally, the DBCO group in this compound enables it to undergo a strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.

DBCO-PEG-Amine (MW 5000) (DBCO-PEG-NH2 (MW 5000)) is a polyethylene glycol (PEG) derivative composed of DBCO, PEG units, and an amine group. The amine can react with other chemical groups, such as carboxyl and aldehyde groups, to form stable chemical bonds. Containing a DBCO group, DBCO-PEG-Amine (MW 5000) can participate in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with molecules that have azide groups.

DBCO-PEG16-NHS ester is a PEG derivative composed of DBCO, PEG units, and an NHS ester. The NHS ester can react with amino acids or other amine-containing molecules. The DBCO group in DBCO-PEG16-NHS ester can engage in a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with azide-containing molecules.

DBCO-PEG-NHS (MW 1000) is a PEG derivative containing DBCO, PEG units, and an NHS ester. The NHS ester can conjugate with amino acids or other amine-containing molecules, while the DBCO group can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.

endo-BCN-PEG4-Boc-amine is a PEG linker that contains a BCN group and a Boc-protected amine. The protected amine can be deprotected under mildly acidic conditions, while the BCN group reacts with azide-labeled biomolecules.

N-(acid-PEG10)-N-bis(PEG10-azide) is a widely utilized PEG reagent featuring a terminal carboxylic acid and two azide groups. Its hydrophilic PEG spacer enhances solubility in aqueous media. The azide groups can react with alkynes, BCN, or DBCO via Click Chemistry to create stable triazole linkages. The terminal carboxylic acid can form robust amide bonds by reacting with primary amine groups in the presence of activating agents such as EDC or HATU.