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azemiglitazone

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Azemiglitazone
MSDC 0602
T46391133819-87-0
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.
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MSDC-0602K
MSDC-0602K, Azemiglitazone potassium
T387151314533-27-1In house
MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). This compound, MSDC-0602K, has potential applications in researching fatty liver conditions, including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K acts as an insulin sensitizer, improving insulinemia and fatty liver disease in mice both individually and in combination with Liraglutide.
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