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By Target- Cytochromes P450
- Glutathione Peroxidase(1)
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Results for "
azd 4831
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- MitiperstatAZD4831T610281933460-19-5Mitiperstat (AZD-4831) is an irreversible, highly selective, oral myeloperoxidase (MPO) inhibitor. Mitiperstat inhibits MPO and thyroid peroxidase (TPO) with IC₅₀ values of 1.5 nM and 0.69 μM, respectively. Mitiperstat exhibits weak inhibition of CYP3A4 with an IC₅₀ of 6 μM. Mitiperstat is suitable for research into diseases such as chronic obstructive pulmonary disease, heart failure with preserved ejection fraction, and non-alcoholic steatohepatitis.
- $158
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