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az31

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • PROTAC Products
    1
    TargetMol | PROTAC
AZ31
AZ-31, AZ 31
T196712088113-98-6In house
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
  • $38
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AZ3146
AZ 3146
T26891124329-14-1
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
  • $35
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AZ'3137
T892382960179-55-7
AZ'3137 (Compound 22) is an orally active PROTAC-based androgen receptor (AR) degrader, exhibiting a DC50 value of 22 nM. It inhibits cell proliferation in LNCaP cells with a GI50 of 74 nM. Additionally, AZ'3137 suppresses AR signaling and tumor growth in a prostate cancer mouse model.
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