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Results for "

az31

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • PROTAC Products
    1
    TargetMol | PROTAC
  • AZ31
    AZ-31, AZ 31
    T196712088113-98-6In house
    AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
    • $38
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  • AZ3146
    AZ 3146
    T26891124329-14-1
    AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
    • $35
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    TargetMol | Citations Cited
  • AZ'3137
    T892382960179-55-7
    AZ'3137 (Compound 22) is an orally active PROTAC-based androgen receptor (AR) degrader, exhibiting a DC50 value of 22 nM. It inhibits cell proliferation in LNCaP cells with a GI50 of 74 nM. Additionally, AZ'3137 suppresses AR signaling and tumor growth in a prostate cancer mouse model.
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