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(2)
By Target- EGFR
- Apoptosis(1)
- BTK(1)
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Results for "
avitinib maleate
" in TargetMol Product Catalog- Inhibitors & Agonists2
avitinib maleate
T37211557268-88-8
Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.
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Avitinib maleate dihydrate
Avitinib maleate dihydrate, AC0010 maleate dihydrate, Abivertinib maleate dihydrate
T2048731822357-78-7
Avitinib (Abivertinib) maleate dihydrate is a third-generation, irreversible, orally active selective EGFR inhibitor with IC50 values of 0.18 nM for EGFRL858R and EGFRT790M, and 7.68 nM for wild-type EGFR. Additionally, Avitinib maleate dihydrate functions as a BTK inhibitor, promoting apoptosis in mantle cell lymphoma cells and inhibiting BTK phosphorylation, demonstrating anticancer properties.
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