atractyloside

1. Atractyloside potassium salt (Atractyloside Dipotassium Salt) inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.

Atractyloside, a natural heteroglucoside found in certain plants like A. gummifera, inhibits mitochondrial ATP synthesis by blocking ADP/ATP translocases, the proteins that facilitate the exchange of adenine di- and triphosphates across the inner mitochondrial membrane.

Atractyloside is a glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and CALLILEPIS. Toxicity is due to inhibition of adenine nucleotide translocase.

Atractyloside (Standard) is a reference standard of Atractyloside intended for quantitative analysis, quality control, and related biochemical research applications.

Carboxyatractyloside (Carboxyatractyloside tripotassium salt) is a natural product. It acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport.

Gummiferin dipotassium exhibits antifungal activity against Saccharomyces cerevisiae and can be used in biochemical experiments and drug synthesis research.

Gummiferin (Standard) is a reference standard for research and analysis in studies involving Gummiferin. Gummiferin dipotassium exhibits antifungal activity against Saccharomyces cerevisiae and can be used in biochemical experiments and drug synthesis research.

Fuscin is a quinonoid fungal metabolite originally isolated from O. fuscum that has diverse biological activities. It inhibits binding of the ADP/ATP translocase inhibitor atractyloside to rat liver mitochondria in an ADP-dependent manner when used at a concentration of 50 μM in a radioligand binding assay. Fuscin (20 μM) reduces the glutathione content of rat liver mitochondria to 28% of controls and inhibits NADH oxidation in sonicated pigeon heart mitochondria preparations in a concentration-dependent manner. It competes with macrophage inflammatory protein 1α (MIP-1α) for binding to CCR5 chemokine receptors in vitro with an IC50 value of 21 μM.