antiandrogenic

p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT

4-Diethylaminobenzaldehyde, a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1), exhibits a potent anti-androgenic effect (IC50: 1.71 μM).

Monobutyl phthalate, the main metabolite of dibutyl phthalate, is an embryotoxin with antiandrogenic properties.

Dienogest (STS 557) is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive.

Edogesterone (PH-218) is a steroid compound characterized by its progestogenic and antiandrogenic properties.

Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.

Monascuspiloin (Monascinol), a compound extracted from rice fermented with Rhodobacter sphaeroides, exhibits antiandrogenic and antitumor activity and inhibits the proliferation of PC-3 and LNCaP.Monascuspiloin improves lipid metabolism and hepatic function in over-alcohol-addicted mice by decreasing hepatic MDA levels and increasing hepatic CAT, SOD and GSH levels.Monascuspiloin has been shown to improve lipid metabolism and hepatic function in over-alcoholized mice. Monascuspiloin regulates the transcription and protein expression of genes related to hepatic lipid metabolism and oxidative stress, and can be used to study alcohol-induced liver injury.

Glycerol Tridecanoate is an orally active precursor (DA precursor) of caprylic acid that can be hydrolyzed to caprylic acid. It is a major component of medium chain triglycerides (MCT) and has antiandrogenic and antihyperglycemic properties. It can be used as an additive in food, pharmaceuticals and cosmetics.

Ludaterone, an antiandrogen agent, exhibits potent antiandrogenic activity.

Glycerol Tridecanoate is an orally active precursor (DA precursor) of caprylic acid that can be hydrolyzed to caprylic acid. It is a major component of medium chain triglycerides (MCT) and has antiandrogenic and antihyperglycemic properties. It can be used as an additive in food, pharmaceuticals and cosmetics.

Cioteronel is an antineoplastic compound with antiandrogenic activities. The antineoplastic action of CPC 10997 appears to be the inhibition of RNA synthesis in vitro. Although it blocks competitively the binding of dihydrotestosterone (DHT) to its protein receptor, it has no significant effects on either estrogen or progesterone receptors.

Dienogest-D6 is a deuterated compound of Dienogest. Dienogest (T2577) has a CAS number of 65928-58-7. Dienogest (T2577) is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive.

Monobutyl Phthalate (Standard) is the standard substance of Monobutyl Phthalate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Monobutyl phthalate, the main metabolite of dibutyl phthalate, is an embryotoxin with antiandrogenic properties.

Tricaprin (Standard) is the standard substance of Tricaprin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Glycerol Tridecanoate is an orally active precursor (DA precursor) of caprylic acid that can be hydrolyzed to caprylic acid. It is a major component of medium chain triglycerides (MCT) and has antiandrogenic and antihyperglycemic properties. It can be used as an additive in food, pharmaceuticals and cosmetics.

Dienogest (Standard) is a reference standard for research and analysis in studies involving Dienogest. Dienogest (STS 557) is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive.

Ganoderic acid DM is an antiandrogenic inhibitor of osteoclastogenesis that markedly suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1). The suppression mediated by Ganoderic acid DM results in the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and a consequent reduction in osteoclast fusion. Ganoderic acid DM is therefore of considerable interest for mechanistic investigations involving osteoclast differentiation, bone remodeling, and androgen-associated signaling pathways in musculoskeletal research models.