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andecaliximab

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Andecaliximab
GS-5745
T768561518996-49-0
Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model of idiopathic pulmonary fibrosis. Andecaliximab can be used to study gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF), as well as dengue virus.
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Anti-MMP9 Antibody
T9901A-1291
Anti-MMP9 Antibody (such as Andecaliximab/GS-5745) is a highly specific neutralizing antibody against Matrix Metalloproteinase-9 (MMP9). By inhibiting the enzymatic activity of MMP9, it effectively prevents extracellular matrix degradation, thereby suppressing tumor invasion, metastasis, and angiogenesis, and has research value in gastrointestinal tumors and inflammatory diseases such as Crohn's disease.
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