amphibian

Dermorphin is agonist of μ-opioid receptor (MOR) agonist.

Dermorphin TFA is a new class of opioids-like peptides

Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.

Litorin is a bombesin derivative derived from amphibians and acts as a bombesin receptor agonist. It induces smooth muscle contraction, stimulates the secretion of gastrin, gastric acid, and pancreatic juice, and inhibits nutrient uptake in in vivo experiments.

Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo.

Granuliberin R, a dodecapeptide derived from the skin of the frog Rana rugosa, is a novel amphibian-origin mast cell degranulating peptide. It has the ability to target rat peritoneal mast cells, prompting them to release granules and histamine [1] [2].

Xenopsin (Xenopsin(2TFA))(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.

Aurein 1.2 is a cationic antimicrobial peptide with antibacterial and anticancer activity. It is active against Gram-positive bacteria (MIC 1–16 μg/mL), fungi, and various human cancer cell lines (NCI-60 panel, IC₅₀ < 10 μM); however, it is unstable once it enters the bloodstream and is easily degraded by proteases.

Xenopsin-Related Peptide 2 (XP-2), an avian analog of amphibian Xenopsin, exhibits efficacy in histamine release from isolated rat mast cells comparable to synthetic Bradykinin [1].

Xenin is a 25 amino acid peptide that has been identified in human gastric mucosa in the search for a counterpart to the amphibian octapeptide xenopsin.

Dermorphin Analog, an analog of Dermorphin, is a natural heptapeptide μ-opioid receptor agonist found in amphibian skin. The dermorphin-derived peptide [Dmt1] Dermorphin Analog labels μ-opioid receptors with high affinity and selectivity in receptor binding assays.

Amphibian bombesin-like peptide

Alytesin acetate is an amphibian bombesin-like peptide.

(D-Arg2, Sar4)-Dermorphin (1-4) is a tetrapeptide derivative of Dermorphin, a peptide found in amphibian skin. It exhibits significant analgesic properties by binding to μ-opioid receptors (MOR) in the body. This compound holds potential for the development of analgesic drugs.