amine peg amine (mw 3400)

Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

DSPE-PEG-Amine, MW 3400 (ammonium), is a phosphoethanolamine involved in the synthesis of liposomal delivery systems. The compound's amino group can be converted into an aromatic aldehyde to react with acetone-protected aromatic hydrazine on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes are formed by creating bis-arylhydrazone (BAH) linkages with the target enzyme molecules, resulting in a liposome-BAH-BCA conjugate that can catalyze the hydration of carbon dioxide into bicarbonate.

Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative capable of self-assembling into micelles, with an extended half-life in vivo. It is useful for drug delivery research.

DOPE-PEG-Amine (MW 3400) is a phospholipid known for its excellent biocompatibility and distinct amphipathic properties. These characteristics make it an ideal and primary excipient or dosage form in pharmaceutical formulations, enabling enhanced therapeutic outcomes. Additionally, DOPE-PEG-Amine (MW 3400) can be utilized in drug delivery research.

Stearic acid-PEG-CH2CO2H (MW 3400) is a lipophilic thiol-reactive PEG polymer. The stearic acid segment is effective for encapsulating hydrophobic therapeutic agents, while the PEG chain enhances overall water solubility and biocompatibility. In the presence of activators such as HATU or EDC, the reaction between carboxylic acid (-COOH) and amine (-NH2) forms stable amide bonds through condensation. Reagent grade, for research use only.