alternaria alternata

Fungi extract, alternaria alternata, is an allergen obtained from samples of the Alternaria alternata species. It is utilized as an allergen in allergy research.

Maculosin is a secondary metabolite of fungi and bacteria.

Oligomycin C is a macrolide antibiotic produced by actinomycetes of the genus Streptomyces and belongs to the oligomycin family. It exhibits significant inhibitory activity against various plant pathogenic fungi, including Aspergillus niger, Alternaria alternata, Botrytis cinerea, and Phytophthora capsici, while showing essentially no antimicrobial activity against bacteria, thereby demonstrating selective antifungal properties.

Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by the fungi Alternaria alternata. It exhibits mutagenic and cytotoxic properties and can mildly disrupt metabolic communication.

Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.

Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.

4'-Demethylpodophyllotoxone, an intermediate in the biotransformation pathway of Alternaria alternata S-f6, undergoes further modification with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP). This modification yields a novel compound that exhibits potent inhibitory effects on the human gastric cancer cell line BGC-823 [1].

(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-Dihydroxy-8-oxo-9-eremophilene-12-oic acid, a phytotoxin recently identified in Alternaria alternata ssp. tenuissima isolates, is linked to fruit spots on apples.

Neoaspergillic acid (NSC 356436) (Compound 2) is a secondary metabolite produced by microorganisms. It is isolated from the endophytic fungus Aspergillus sp. SPH2 and exhibits potent antifungal activity against Alternaria alternata, Botrytis cinerea, and Fusarium oxysporum. This compound appears during the exponential growth phase of fungi and also shows antitumor and antibacterial properties.

A mixture of (E)-octadecyl p-coumarate and (Z)-octadecyl p-coumarate has antifungal activity , it shows the dose dependent inhibition of the spore germination of Alternaria alternata and A. porri.