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ailanthone

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
  • Natural Products
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    TargetMol | Natural_Products
Ailanthone
Δ13-Dehydrochaparrinone
TQ0209981-15-7
Ailanthone (AIL) is a natural compound derived from the tree Ailanthus altissima and has anti-hepatocellular carcinoma (HCC) properties. It can induce G0/G1 phase cell cycle arrest by downregulating the expression of cyclins and CDKs, while upregulating the expression of p21 and p27. Additionally, Ailanthone is a potent androgen receptor (AR) inhibitor, capable of inhibiting both the full-length androgen receptor (IC50: 69 nM) and constitutively active splice variants (IC50: 309 nM).
  • $36
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TargetMol | Citations Cited
2-Dihydroailanthone
TN8862
2-Dihydroailanthone is a natural product that can be used in related research in the field of life sciences. Its product number is TN8862.
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7-10 days
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