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(2)
By Target- Dehydrogenase
- Isocitrate Dehydrogenase (IDH)(1)
- Opioid Receptor(1)
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Results for "
ag120
" in TargetMol Product Catalog- Inhibitors & Agonists3
Ivosidenib
AG-120
T36171448347-49-6
Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular differentiation and inhibit cellular proliferation in IDH1-expressing tumor cells.
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(R,S)-Ivosidenib
(R,S)-AG-120
T134382070009-31-1
(R,S)-Ivosidenib is the less active enantiomer of Ivosidenib .
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AG-120 (racemic)
T222531448346-63-1
AG-120 (racemic), the racemic mixture of AG-120, is an orally available isocitrate dehydrogenase type 1 (IDH1) inhibitor, and shows potential antineoplastic activity.
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