aep

17-AEP-GA is an HSP90 antagonist, a potent inhibitor of glioblastoma cell proliferation, survival, migration, and invasion, and a toxic component of antibody-coupled activated molecules (ADCs), which can be used to study glioblastomas.

δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.

(2-Aminoethyl)phosphonic acid (2-Aminoethylphosphonic acid) is primarily detected in urine. (2-Aminoethyl)phosphonic acid participates in many enzymatic reactions and is also the parent compound of other transformation products, including but not limited to ceramide 2-(methylamino)ethylphosphonate, N-(2-phosphineethyl)cholamide and CMP-2-aminoethylphosphonate.

APE-IN-1 can be used for the early diagnosis and drug research of Alzheimer's disease. APE-IN-1 is a potent Asparagine endopeptidase (AEP) inhibitor with IC 50 value of 89 nM [1].

AEP-IN-2 is an inhibitor of asparagine endopeptidase (AEP) that prevents the cleavage of APP and Tau by AEP. It is orally active and reduces levels of Aβ40, Aβ42, and p-Tau [1].

AEP-IN-3 (compound 18) is an orally administered, potent asparagine endopeptidase (AEP) inhibitor that effectively crosses the blood-brain barrier. It boasts an IC50 of 7.8 ± 0.9 nM and is applicable in Alzheimer's Disease (AD) research [1].

Mal-VC-PAB-ABAEP-Azonafide, an ADC (antibody-drug conjugate) linker-drug conjugate, demonstrates potent antitumor activity. It incorporates Azonafide, a cytotoxin, connected through the ADC linker Mal-VC-PAB[1].

NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor.

Naepaine hydrochloride is a biochemical.

Suc-AEPF-AMC (Suc-Ala-Glu-Pro-Phe-AMC) is a peptide substrate for the peptidyl prolyl isomerases Pin1 and Par14, and is a peptide compound that can be used to assay protease activity.

Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.

Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.

16,17-Epoxypregnenol is a useful organic compound for research related to life sciences. The catalog number is T3222 and the CAS number is 974-23-2.

16a,17a-Epoxy-4-Pregnen-3,20-Dione is a synthetic progestin, a metabolite of the luteinizing hormone hormone, which acts by binding to the luteinizing hormone receptor. It has been used to study the effects of progesterone on reproductive organs, the effects of the hormone on cell growth and development, and the effects of the hormone on the immune system.

16,17-Epoxypregnenolone acetate (16alpha,17alpha-Epoxypregnenolone acetate) can be produced by Burkholderia cepacia SE-1.

CHALCONE ALPHA,BETA-EPOXIDE, with CAS No. 5411-12-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. CHALCONE ALPHA,BETA-EPOXIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Amiphos are residues in food.

16beta-Methyl-16alpha,17alpha-epoxypregnenolone serves as a pharmaceutical intermediate.

Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE application.

mp-dLAE-PABC-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs) that incorporates the potent tubulin inhibitor Monomethyl auristatin E (MMAE). This compound is utilized in the synthesis of ADCs to deliver targeted cytotoxic treatment [1].

MMAE-PAB(p-glucuronide)-PEG3-aminooxy is a compound with potential for drug delivery applications.

5β,6β-Epoxycholestanol is an oxidative metabolite of cholesterol produced through radical and non-radical oxidation at the 5,6-double bond. It induces the release of lactate dehydrogenase (LDH) and apoptosis in differentiated macrophage U937 cells. This compound has been identified in human fatty streaks and advanced atherosclerotic lesions but is absent in normal aortic tissue.

11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28,13β-olide is a natural product from Paeonia lactiflora.

1beta,10beta-Epoxydehydroleucodin is a natural product for research related to life sciences. The catalog number is TN2667 and the CAS number is 130858-00-3.