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Results for "
adamts5 inhibitor
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- ADAMTS-5 InhibitorT14124929634-33-3ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 µM and can be used in studies about cartilage destruction in arthritis.
- $40
SizeQTY - ADAMTS-5-IN-4T214928ADAMTS-5-IN-4 (Compound 4b) is a selective inhibitor of ADAMTS5 with an IC₅₀ of 9.4 μM. It significantly hinders Aggrecan degradation in explant models of osteoarthritis and effectively suppresses pseudopodia extension and directional migration in ovarian cancer cells. ADAMTS-5-IN-4 also exhibits significant cytotoxicity towards HEK293T cells, human chondrocytes, and porcine cartilage explants. This compound is applicable in research related to osteoarthritis and ovarian cancer.
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