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By Target- Cytochromes P450
- Androgen Receptor(1)
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Results for "
abiraterone
" in TargetMol Product Catalog- Inhibitors & Agonists10
- Isotope Products1
Abiraterone
Cited
CB-7598
T6216154229-19-3
Abiraterone (CB-7598) (CB-7598) is an effective steroidal cytochrome P450 17alpha-hydroxylase-17, 20-lyase (CYP17) inhibitor (IC50: 4 nM).
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CitedAbiraterone Acetate Cited
Zytiga, CB7630
T6215154229-18-2
Abiraterone Acetate (CB7630) is an androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.
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CitedAbiraterone metabolite 1
3β-OH-5α-Abi
T135251940176-03-3In house
Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.
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Abiraterone decanoate
T634342486052-18-8
Abiraterone decanoate is a prodrug of Abiraterone that provides controlled release and long-lasting CYP17 inhibition of Abiraterone using intramuscular (IM) delivery.
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Abiraterone N-oxide
T746852378463-76-2
Abiraterone N-oxide, a metabolite of Abiraterone, serves as a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1].
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Abiraterone sulfate
T746841993430-25-3
Abiraterone sulfate, a metabolite of Abiraterone, is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity [1].
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Abiraterone sulfate N-oxide
T832141993430-24-2
Abiraterone sulfate N-oxide, a carboxylic acid and major metabolite of Abiraterone, is utilized in prostate cancer research [1] [2].
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D4-abiraterone
Δ4-Abiraterone, CB-7627, Abiraterone D4A metabolite
T10946154229-21-7
D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abiraterone is also an antagonist of androgen receptor.
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Abiraterone-d4
TMIJ-01352122245-62-7
Abiraterone-d4 is a deuterated compound of Abiraterone. Abiraterone has a CAS number of 154229-19-3. Abiraterone (CB-7598) is an effective steroidal cytochrome P450 17alpha-hydroxylase-17, 20-lyase (CYP17) inhibitor (IC50: 4 nM).
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5,6-Dihydroabiraterone
T74094219843-75-1
5,6-Dihydroabiraterone, a metabolic derivative of Abiraterone, is a potent and irreversible inhibitor of CYP17A1, exhibiting antiandrogen and antitumor activities, particularly effective against castration-resistant prostate cancer (CRPC) [1] [2].
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