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By Target- Akt
- CDK(1)
- ERK(1)
- PKA(1)
- PKC(1)
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Results for "
a 674563 2hcl(552325 73 2(fb 2hcl))
" in TargetMol Product Catalog.- Inhibitors & Agonists1
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- A-674563 HCl (552325-73-2(free base))
T44442070009-66-2A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in th- $77
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