T4056

Hygric acid (N-Methyl-L-proline) is a proline analogue found in citrus juices and bergamot juice.

Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models. It acts as a potent inhibitor of DNA (cytosine-5)-methyltransferase (Mtase) with an IC50 of 8.4 μM.

ThrRS-IN-2 is an inhibitor of threonyl-tRNA synthetase (ThrRS), exhibiting an inhibition concentration (IC50) value of 56.5 ± 3.5 μM.

24-Methylenecycloartanyl ferulate, a compound belonging to the γ-oryzanol family, demonstrates the ability to enhance parvin-beta expression within human breast cancer cells. Furthermore, it exhibits potential as an ATP-competitive Akt1 inhibitor, with an EC 50 value of 33.3 μM.

Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris . Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro.

5MPN is an orally active and selective inhibitor of 6-phosphofructokinase-2-kinase (PFKFB4) that competitively inhibits the F6P binding site and inhibits the proliferation of myeloma cells, and can be used in the study of myeloproliferative neoplasms.

2'-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a modified nucleoside, can be enzymatically converted from 2'-O-(2-methoxyethyl)-2,6-diaminopurine riboside by adenosine deaminase; however, it is not readily phosphorylated by cytosolic nucleoside kinases and cannot be incorporated into cellular DNA or RNA.

Fmoc-MMAE, a protective group-conjugated variant of monomethyl auristatin E (MMAE), serves as a powerful inhibitor of tubulin. It finds application in the synthesis of antibody-drug conjugates (ADC).