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(1)
By Target- DNA/RNA Synthesis
- NUDIX hydrolase(1)
- Others(1)
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Results for "
T39785L
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- TH5427T39785L2253744-56-6TH5427 is a lead NUDT5 inhibitor(MG assay IC50 = 29 nM).
- $98
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Other Forms of Products
- TH5427 hydrochloride
T397852253744-57-7TH5427 hydrochloride is a potent and selective inhibitor of NUDT5 with an IC50 of 29 nM. It demonstrates a remarkable 690-fold selectivity towards NUDT5 compared to MTH1. Moreover, TH5427 hydrochloride effectively inhibits progestin-dependent, PAR-derived nuclear ATP synthesis in breast cancer cells, thereby impeding chromatin remodeling, gene regulation, and ultimately suppressing proliferation.- $693
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