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By Target- PROTAC Linker
- ALK(3)
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Results for "
T1661
" in TargetMol Product Catalog.- Inhibitors & Agonists13
- PROTAC Products10
- Isotope Products1
- ADC/ADC Related1
Crizotinib
Cited
PF-02341066
T1661877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.
- $29
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QTY
CitedPropargyl-PEG3-OCH2-Boc
T16610888010-02-4
Propargyl-PEG3-OCH2-Boc is a polyethylene glycol (PEG)-derived linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
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Propargyl-PEG3-phosphonic acid diethyl ester
T166111052678-30-4
Propargyl-PEG3-phosphonic acid diethyl ester, a PEG-based PROTAC linker, is employed for the synthesis of PROTACs[1].
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Propargyl-PEG3-phosphonic acid
T166121714139-62-4
Propargyl-PEG3-phosphonic acid, a PEG-based PROTAC linker, is utilized for PROTAC synthesis[1].
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Propargyl-PEG4-5-nitrophenyl carbonate
T166131422540-81-5
Propargyl-PEG4-5-nitrophenyl carbonate is a polyethylene glycol (PEG) derivative designed as a linker for proteolysis targeting chimeras (PROTACs) synthesis [1].
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Propargyl-PEG4-acid
T166141415800-32-6
Propargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and its analogue PROTAC 3. PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells[1].
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Propargyl-PEG4-alcohol
T1661587450-10-0
Propargyl-PEG4-alcohol is a PEG-based linker for PROTACs that joins two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Propargyl-PEG4-amine
T166161013921-36-2
Propargyl-PEG4-amine, a PEG-based PROTAC linker, can be used in the synthesis of PROTACs.
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Propargyl-PEG4-beta-D-glucose
T166171397682-63-1
Propargyl-PEG4-beta-D-glucose is a polyethylene glycol (PEG) derivatized PROTAC linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
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Propargyl-PEG4-Boc
T166181355197-66-8
Propargyl-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands to facilitate PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
- $30
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QTY
Propargyl-PEG4-Br
T166191308299-09-3
Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
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Crizotinib acetate
PF-2341066, PF2341066, PF-02341066, PF02341066, PF 02341066
T1661L877399-53-6
Crizotinib, an orally bioavailable agent, belongs to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity.
- $1,670
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QTY
Crizotinib-D5
TMIJ-01151395950-84-1
Crizotinib-D5 is a deuterated compound of Crizotinib. Crizotinib (T1661) has a CAS number of 877399-52-5. Crizotinib (T1661) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.
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